This publication describes the development of platelet-derived growth factor (PDGF) - derived peptides, subjected to concatemerisation. The construct demonstrates possesses promising pro-regenerative potential. It was developed as a result of a collaboration between the BioVentures Institute, the University of Gdańsk, the Medical University of Gdańsk, and Gdańsk University of Technology, funded by the NCBR grant TECHMATSTRATEG2/410747/11/NCBR/2019 (2019–2023).
This publication describes the development of a breakthrough thermophilic variant of phage display technology. The platform is further enhanced by integration with DNA FACE™ technology. It was developed as a result of a collaboration between the BioVentures Institute, the University of Gdańsk, the Medical University of Gdańsk, and Gdańsk University of Technology, funded by the NCBR grant TECHMATSTRATEG2/410747/11/NCBR/2019 (2019–2023).
Prof. dr hab. Piotr Mariusz Skowron (University of Gdansk) has received National Center for Science (NCN) grant in the amount of 2,197,200 PLN for the development of novel gene expression system, based on thermophilic bacteriophages entitled: “Synthetic biology approach to biosynthesis of termophilic, problematic and toxic protein: bacteriophage expression system with very wide temperature range (30-80).”. Cloning and expression of genes in heterologous organisms, synthetic biology, and recombinant proteins have become indispensable tools in scientific research and the biotechnology industry. However, some essential areas of gene cloning/expression suffer from major deficiencies, such as problems with protein biosynthesis from recombinant genes. Selected concepts of of the DNA FACE™ technology will be applied in prospective genetic constructs.