Patents

BioVentures Institute patents, patent applications, publications and manuscripts related to the DNA fragment amplification-expression technology and concatemeric proteins of genetically programmable function:

Patents Granted:

1. Skowron P, Zylicz-Stachula A, Zolnierkiewicz O, Skowron M, Janus L, Jezewska-Frackowiak J, Krefft D, Nidzworski D, Szemiako K, Maciejewska N, Nowak M, Szymanska A: A method of obtaining a polyepitopic protein as well as a DNA vector for embodying this method. European Patent Office no EP 3 134 426 B1 (2020).

2. Skowron P, Zylicz-Stachula A, Zolnierkiewicz O, Skowron M, Janus L, Jezewska-Frackowiak J, Krefft D, Nidzworski D, Szemiako K, Maciejewska N, Nowak M, Szymanska A: A method of obtaining a polyepitopic protein as well as a DNA vector for embodying this method. Japanese Patent Office no P6692796 (2020).

3. Skowron P, Zylicz-Stachula A, Zolnierkiewicz O, Skowron M, Janus L, Jezewska-Frackowiak J, Krefft D, Nidzworski D, Szemiako K, Maciejewska N, Nowak M, Szymanska A: A method of obtaining a polyepitopic protein as well as a DNA vector for embodying this method. United States Patent Office no US 10,874,735 B2 (2020).

4. Skowron P, Zylicz-Stachula A, Zolnierkiewicz O, Skowron M, Janus L, Jezewska-Frackowiak J, Krefft D, Nidzworski D, Szemiako K, Maciejewska N, Nowak M, Szymanska A: A method of obtaining a polyepitopic protein as well as a DNA vector for embodying this method. Israel Patent Office no 248011 (2021).

5. Skowron P, Zylicz-Stachula A, Zolnierkiewicz O, Skowron M, Janus L, Jezewska-Frackowiak J, Szymanska A: Sposób uzyskiwania białka poliepitopowego oraz wektor DNA do realizacji tego sposobu. (Eng.: A method of obtaining a polyepitopic protein as well as a DNA vector for embodying this method.) Republic of Poland Patent Office no 228341 (2018). 


Patent applications:
 

1. Skowron P, Zylicz-Stachula A, Zolnierkiewicz O, Skowron M, Janus L, Jezewska-Frackowiak J, Krefft D, Nidzworski D, Szemiako K, Maciejewska N, Nowak M, Szymanska A: A method of obtaining a polyepitopic protein as well as a DNA vector for embodying this method. China Patent Office no CN 106488983 A (2016).

2. Skowron P, Zylicz-Stachula A, Zolnierkiewicz O, Skowron M, Janus L, Jezewska-Frackowiak J, Krefft D, Nidzworski D, Szemiako K, Maciejewska N, Nowak M, Szymanska A: A method of obtaining a polyepitopic protein as well as a DNA vector for embodying this method. Indian Patent Office no 201647039411 (2016).

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Publications

1. Skowron PM, Krawczun N, Żebrowska J, Krefft D, Żołnierkiewicz O, Bielawa M, Jeżewska-Frąckowiak J, Janus Ł, Witkowska M, Palczewska M, Schumacher A, Wardowska A, Deptuła M, Czupryn A, Mucha P, Piotrowski A, Sachadyn P, Rodziewicz-Motowidło S, Pikuła M, Zylicz-Stachula A: A vector-enzymatic DNA fragment amplification-expression technology for construction of artificial, concatemeric DNA, RNA and proteins for novel biomaterials, biomedical and industrial applications. Materials Science & Engineering: C  (2020) 108:110426.

2. Skowron PM, Krawczun N, Żebrowska J, Krefft D, Żołnierkiewicz O, Bielawa M, Jeżewska-Frąckowiak J, Janus Ł, Witkowska M, Palczewska M, Schumacher A, Wardowska A, Deptuła M, Czupryn A, Mucha P, Piotrowski A, Sachadyn P, Rodziewicz-Motowidło S, Pikuła M, Zylicz-Stachula A: An efficient method for the construction of artificial, concatemeric DNA, RNA and proteins with genetically programmed functions, using a novel, vector-enzymatic DNA fragment amplification-expression technology. MethodsX 7, 2020, 7:101070.

3. Skowron PM, Krawczun N, Żebrowska J, Krefft D, Żołnierkiewicz O, Bielawa M, Jeżewska-Frąckowiak J, Janus Ł, Witkowska M, Palczewska M, Zylicz-Stachula A: Data regarding a new, vector-enzymatic DNA fragment amplification-expression technology for the construction of artificial, concatemeric DNA, RNA and proteins, as well as biological effects of selected polypeptides obtained using this method. Data in Brief  (2020) 28:105069.

4. Skowron PM, Kropinski AM, Zebrowska J, Janus L, Szemiako K, Czajkowska E, Maciejewska N, Skowron M, Łoś J, Łoś M, Zylicz-Stachula A: Sequence, genome organization, annotation and proteomics of the thermophilic, 47.7-kb Geobacillus stearothermophilus bacteriophage TP-84 and its classification in the new Tp84virus genus. PLOS ONE (2018), 13: e0195449.

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